Sarah Silverman brought depth and charm to her role as Helen in Masters of Sex, Showtime’s drama about pioneering sex researchers William Masters and Virginia Johnson. Introduced in Season 2, Helen is a palm reader and the former lover of Betty (played by Annaleigh Ashford), and her storyline explores the challenges of being in a same-sex relationship in the 1960s. Silverman reprised her role in Season 3, where Helen and Betty attempt to start a family, navigating societal obstacles and personal struggles2. Her performance added emotional weight to the series, showcasing her ability to balance humor with heartfelt moments.